After kidney donation by a healthy individual, or the removal of one diseased kidney, the remaining kidney often increases in function and growth to compensate for this loss.
The mechanism that drives this still remains elusive.
Flinders University Professor Jonathan Gleadle will delve deeper by using a Flinders Foundation Health Seed Grant to better understand how one kidney grows when its ‘mate’ is removed.
The project will use novel genetic tools to identify key components that lead to healthy kidney growth, in the hope that it may one day provide novel targets for drug interventions for people with impaired kidney function.
This research is made possible thanks to a generous supporter and donations from the community.
Project title: Does circulating miRNA drive healthy Renal Compensatory Hypertrophy?
Lead researcher: Professor Jonathan Gleadle
Flinders Foundation acknowledges the Kaurna people as the traditional custodians of the land on which the Flinders precinct was established. We acknowledge the Kaurna people’s deep and ongoing connection to land, waters and community, and pay our respect to their Elders, past and present.